Aging is a biological process that occurs in each of us as individuals and is accompanied by a variety of changes. At the molecular level, DNA methylation occurs, a process in which a methyl group is covalently bonded at the cytosine 5 carbon position of a genomic CpG dinucleotide, and the association between DNA methylation and aging has been extensively studied and their close correlation has been found.
DNA methylation is an epigenetic modification that plays a key role in many aging-related biological processes. Based on this, we can use DNA methylation analysis for related studies, such as age prediction, disease risk prediction, and aging mechanism exploration.
Longevity Interventions Evaluation Using DNA Methylation
A number of interventions may be able to prevent age-related diseases and extend lifespan, including dietary, pharmacological and genetic, and the effects of interventions to delay aging and increase longevity can be assessed based on age-related DNA methylation changes.
