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Quantifying the resulting mechanical parameters is critical for clarifying the mechanical consequences caused by the changed cell wall composition. We are committed to providing our customers with services for the characterization of mechanical properties of plant cell walls and submitting detailed and scientific experimental reports to customers.Background of mechanical properties of cell wall analysis servicesThe cell wall has long been of interest to researchers because of its unique mechanic...
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Laboratory equipment is a general term for the various instruments, containers and other tools needed for operation, synthesis, and analysis in various laboratories. The equipment helps researchers to observe, test, experiment or analyze data to confirm the authenticity or rationality of scientific hypotheses. According to the scope of application, laboratory equipment can be divided into general equipment and specialized equipment.General laboratory equipment includes freezers, incubators, shak...
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Silica-based vectors are attractive as gene transfer vehicles due to their high stability, safety, and ease of structural and surface modification. A variety of silica-based vectors for gene delivery have been reported, including silica nanotubes (SNT), silica sheets, and silica NPs (solid (non-porous) silica NPs and porous silica NPs). Among these, silica NPs have been extensively investigated by researchers as carriers with many useful and attractive properties.Several reports have been publis...
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In the field of scientific research, understanding and studying emotion-related behaviors in animals plays a crucial role in advancing the knowledge of the human brain and mental health. Animal models can help researchers better comprehend animal behaviors, and rodent models in particular have become important objects for understanding the mechanisms of emotional behaviors and exploring new treatments for emotion-related disorders including anxiety, depression, and stress. With their remarkable ...
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The aging of today's global population is accelerating, leading to a higher incidence of some diseases related to aging, such as chronic diseases, neurodegenerative diseases, cardiovascular diseases, etc. However, people at the same age may show different disease expressions, and one possible factor is due to differences in the aging process of different individuals, which means that the actual age of individuals is the same but their biological age may be different.Then understanding the biolog...
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The diagnosis and treatment of rare diseases have long been a daunting challenge due to their complex and often undefined nature. However, with recent advancements in technology, specifically in the realm of genomics, whole genome sequencing (WGS) has emerged as a powerful tool that has revolutionized the diagnosis and management of rare diseases. This groundbreaking technique offers hope to countless individuals and their families who have suffered from the uncertainties and lack of answers ass...
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The importance of nucleic acids in controlling life processes is well known. Under the suitable conditions, DNA molecules are responsible for replication of themselves and acts as templates for RNA synthesis in transcription. In translation, RNA molecules control protein synthesis and thus various metabolic activities in living cells. All these processes are monitored by sequences of bases in polynucleotide chains. Nucleosides consist of a sugar group and a heterocyclic nucleobase that bound to ...
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What is cystic fibrosis?Cystic fibrosis (CF) is a rare genetic disorder that affects the lungs, digestive system, and other organs. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a protein that regulates chloride ions transport across cell membranes. These mutations cause the CFTR protein to be either absent or not function properly, leading to the buildup of thick, sticky mucus in the lungs, pancreas, and other organs. Treatment o...
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Biofilm Construction ServicesBacterial biofilm formation is a complex developmental process involving multiple stages, including migration and initial attachment, EPS production and irreversible attachment, maturation, disruption, and cell dispersion. In most environments, the mechanism of infection and pathogenesis is a continuous interaction between the host and the microorganism, as well as between the microorganisms themselves. These interactions can influence and determine the fate of infec...
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Research on Psychiatric MechanismsMolecular biology analysis in psychiatry is an approach that relies on biological techniques at the molecular level to study psychiatric disorders. It includes the study of expression profiles, DNA, RNA, proteins, and metabolites at the molecular level.Our molecular biology analysis can also be applied to study the development of novel drugs. For example, by modulating one or more genes, proteins, and metabolic pathways to develop a novel drug and analyze its ef...
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Gene deletion is the process of removing one or more genes from an organism's genome. This technique is commonly used in genetic research to study the function of specific genes and their role in various biological processes like strain engineering. Gene deletion can be achieved through several methods, including CRISPR/Cas9 gene editing, homologous recombination, and transposon-mediated mutagenesis.Services for Gene DeletionOur gene deletion services are designed to help researchers study the f...
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Amerigo Scientific offers four series of ion exchange (IEX) chromatography resins of different matrix type and pore size to satisfy a variety of applications. These products are complementary with each other and are solutions of all process steps (capture, intermediate purification, and polishing) in chromatography for purifications of a variety of substances from small peptides to large proteins and viral particles.Uni Series IEX ResinsUniCM, UniSP, UniQ, UniDEAE, and UniMSP are designed for th...
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Samples superbug identificationBacteria are becoming resistant to antibiotics at an alarming rate, posing a major threat to our health care. Rapidly identifying the bacteria that cause specific infections is critical to preventing the development of antibiotic resistance. However, many researchers may face some challenging processes in superbug identification techniques.Rapid Detection of Superbugs Using PhagesPhages offer a unique opportunity for superbug detection. Using the ability of phages ...
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Turgor pressure measurement servicesTurgor pressure, also known as hydrostatic pressure, is the pressure on the cell wall generated by the expansion of a plant cell due to the volume of water absorbed. Turgor pressure is of physiological importance to plant growth. Not only does it maintain cellular tension and keep the plant in its natural posture, it also regulates the opening and closing of stomata. The growth of plant cells is thought to be the result of a finely tuned interaction between tu...
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Introduction of TME biomarker detection servicesTumor markers appear along with tumors and are usually increased in amounts of proteins, oncogenes, tumor suppressor genes and their related products in the form of antigens, enzymes, receptors, hormones or metabolites. It is produced and secreted by tumor cells, or is part of the released tumor cell structure. It exists only in tumor cells and is often released into serum or other body fluids, which can reflect the presence of tumors in the body t...
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Telomere length is highly heterogeneous and varies with cell type, age, and individual. Most current measurements of telomere length use the average of cell populations. However, it is worth noting that methods to quantify the length of individual telomeres can provide valuable information about telomere length distribution.Telomere Length Measurement in Single Cells Extremely short telomeres are usually the cause of age-related pathology. The longest telomeres are markers of the adult stem cell...
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Radionuclide Drug Conjugate DesignRDC (Radionuclide Drug Conjugate) is an innovative and rapidly evolving multifunctional radiopharmaceutical. Composed of four components, including radionuclide, chelator, linker, and targeting molecule, RDC can accurately identify the diseased cells, image the binding cells, and damage the tumor.Bifunction of RDCDiagnostic ImagingNuclear imaging, providing detailed imaging at the molecular and cellular level, can accurately diagnose and analyze cancer. Both PET...
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Cells play an important role in both pathological studies of stroke and in the development of therapies. In pathological studies, on the one hand, we provide a preliminary understanding of the pathological mechanisms of stroke by establishing different stroke models based on brain cells. On the other hand, we elaborate the role of stroke on different cells through the study of different cells in in vivo models. In therapeutic development, stem cell-based stroke therapy has been shown to be effec...
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Background Metabolic rare diseases are diseases that result from some defect or abnormality in the metabolic process. These diseases are usually caused by genetic factors and affect the body's metabolic processes, such as protein, carbohydrate, and lipid metabolism. Metabolic rare diseases usually lead to serious health problems, including muscle wasting, liver disease, neurological damage, and more. Due to the rarity and complexity of these diseases, sophisticated research tools and techniques ...
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Exosomes are the smallest and most characteristic of extracellular vesicles and contain a variety of biological information, including proteins, lipids, DNA, mRNA, and microRNA. These biomolecules are involved in regulating various life activities such as signal transduction, proliferation, migration, and angiogenesis among tumor cells. Exosomes are not only a new biological marker assay, but also provide potential molecular therapeutic targets and are expected to be a carrier for anti-brain tum...
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Cancer-Associated Fibroblasts (CAFs) Cancer-associated fibroblasts, or CAFs, are a type of stromal cell commonly found in the tumor microenvironment. They are associated with all stages of cancer and contribute to its progression in various ways. CAFs can increase the rate of cancer cell growth, promote the formation of new blood vessels, and facilitate the spread of cancer cells to other parts of the body.In addition to these effects, CAFs can also suppress the immune system's ability to fight ...
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Neoantigen is a kind of tumor-specific antigen derived from non-synonymous mutations, which plays an important role in the killing of tumor by immune cells, and effective anti-tumor immunity is directly related to tumor neoantigen-specific T cells. Neoantigens are highly immunogenic and specific, not expressed in normal tissues, and bypass the central thymus without immune tolerance, making them ideal targets for anti-tumor immunotherapy. With the development of next-generation sequencing techno...
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Biofilm is a complex, multi-dimensional spatial structure composed of microorganisms and their extracellular polymers adhered to the surface of living or non-living bodies, and is ubiquitous in nature. Biofilms are increasingly detected in patients with infectious diseases or in animal models. The relationship between the formation of biofilm and infectious diseases and its role in the occurrence, development and prognosis of diseases have become a hot research topic in recent years. At present,...
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In recent years, vaping has emerged as a popular alternative to traditional smoking, offering a wide array of products and flavors to suit individual preferences. Whether you're a seasoned vaper or new to the scene, finding the best vape products and flavors can enhance your experience and satisfaction. Let's delve into the world of vaping and explore some top picks in both categories.Best Vape Products:Pod Systems: Pod systems have gained immense popularity for their portability and user-friend...
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