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Introduction to Protein DesignProtein design aims to create proteins with enhanced or novel activity, behavior, or other functional properties. As a powerful tool, it may have a profound impact on synthetic biology and may have more rapid and innovative applications. In the near future, protein design, especially computational design, will greatly expand the functional capabilities of synthetic cells. De Novo Protein DesignIn de novo protein design, the ultimate objective is to identify the appr...

Introduction of The Cerebral CortexThe cerebral cortex is the outermost layer of tissue in the brain that is only a few millimeters thick. The appearance of the folds increase the surface area of the cerebral cortex, which contains between 14 billion and 16 billion neurons, thus allowing it to play an important role in human cognitive function, while controlling somatic movements and interpreting sensations.Injuries Caused by Cortical Function DeclineCerebral Cortex DisordersThe cerebral cortex,...

Introduction to Genetic CircuitSynthetic biology is a field of science that deals with engineering and redesigning biological systems. The design of genetic circuits is inspired by electronics and computer science. Genetic circuits can perform logical functions mimicking those observed in electronic circuits and exhibit control over the flow of information in biological systems. Genetic circuit design should follow the principles of modularity, orthogonality, predictability, and reliability.In r...

Turgor pressure measurement servicesTurgor pressure, also known as hydrostatic pressure, is the pressure on the cell wall generated by the expansion of a plant cell due to the volume of water absorbed. Turgor pressure is of physiological importance to plant growth. Not only does it maintain cellular tension and keep the plant in its natural posture, it also regulates the opening and closing of stomata. The growth of plant cells is thought to be the result of a finely tuned interaction between tu...

High-performance liquid chromatography (HPLC) columns are used for the analysis or preparation of separated compounds from complex mixtures. The pressurized liquid solvent containing the sample mixture passes through a column filled with a solid adsorbent material. Since each component in the sample interacts with the adsorbent material slightly differently, the components with different flow rates are separated as they flow out of the column. According to separation mechanism, common HPLC colum...

Introduction of TME biomarker detection servicesTumor markers appear along with tumors and are usually increased in amounts of proteins, oncogenes, tumor suppressor genes and their related products in the form of antigens, enzymes, receptors, hormones or metabolites. It is produced and secreted by tumor cells, or is part of the released tumor cell structure. It exists only in tumor cells and is often released into serum or other body fluids, which can reflect the presence of tumors in the body t...

Cells play an important role in both pathological studies of stroke and in the development of therapies. In pathological studies, on the one hand, we provide a preliminary understanding of the pathological mechanisms of stroke by establishing different stroke models based on brain cells. On the other hand, we elaborate the role of stroke on different cells through the study of different cells in in vivo models. In therapeutic development, stem cell-based stroke therapy has been shown to be effec...

Research on Psychiatric MechanismsMolecular biology analysis in psychiatry is an approach that relies on biological techniques at the molecular level to study psychiatric disorders. It includes the study of expression profiles, DNA, RNA, proteins, and metabolites at the molecular level.Our molecular biology analysis can also be applied to study the development of novel drugs. For example, by modulating one or more genes, proteins, and metabolic pathways to develop a novel drug and analyze its ef...

Neoantigen is a kind of tumor-specific antigen derived from non-synonymous mutations, which plays an important role in the killing of tumor by immune cells, and effective anti-tumor immunity is directly related to tumor neoantigen-specific T cells. Neoantigens are highly immunogenic and specific, not expressed in normal tissues, and bypass the central thymus without immune tolerance, making them ideal targets for anti-tumor immunotherapy. With the development of next-generation sequencing techno...

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Home AppliancesHome appliances are considered as household machines that help in performing household work like cleaning, cooking, mixing, and food storage.Samsung Washing MachineIn the future, it is predicted that these technological advances and the development of electronic appliances will increase the market, in the upcoming years the expendable cash of consumers will be high because living standards are improving, increasing the quality of life, and making work easy in the home by using the...

The analysis of impurities in drugs is a very important part. This paper focuses on the important role of the source analysis of impurities and focuses on the development of analytical techniques in the process of impurity research, especially the development of mass spectrometry technology in structure identification. Source analysis of impuritiesImpurities in a drug can arise from manufacturing as well as distribution. According to ICH guidelines, drug impurities can be divided into organic im...

Introduction of Strain HybridizationOne of the key components of synthetic biology is the creation of novel strains with unique properties that can be used for various applications such as biotechnology, medicine, and agriculture. Strain hybridization is an essential technique in synthetic biology that involves the combination of genetic material from different strains to create a new hybrid strain with desired traits.  

Introduction of customization of aging Animal models Available Models of Common Age-Related DiseasesBone disease. For example, age-related bone loss, and age-related osteoporosis models.Cardiovascular diseases. For example, the primary hypertension animal model, myocardial infarction animal model, heart failure animal model, etc.Aging lung.Neurodegenerative disease. For example, models of Parkinson's disease and Alzheimer's disease.Multi-morbidity and frailty. For example, some chronic disease m...

The aging of today's global population is accelerating, leading to a higher incidence of some diseases related to aging, such as chronic diseases, neurodegenerative diseases, cardiovascular diseases, etc. However, people at the same age may show different disease expressions, and one possible factor is due to differences in the aging process of different individuals, which means that the actual age of individuals is the same but their biological age may be different.Then understanding the biolog...

The Synthetic Biology Platform is a comprehensive toolbox and fully integrated platform to empower synthetic biology research and development. The Synthetic Biology Platform is a comprehensive toolbox and fully integrated platform to empower synthetic biology research and development. Synthetic biology is an emerging interdisciplinary field that combines principles of engineering and biology to create artificial lives or re-design organisms for useful purposes. In fact, designing a platform that...

ethylation-Based Biological Age and Cancer RiskChanges in DNA methylation levels with age, and it has been widely studied as a well-known biomarker of aging. A number of DNA methylation age clocks have appeared and been used, and when the age predicted by the methylation clock is greater than the actual age, it is considered to have "age acceleration", which is also called the biological measure of aging.Research suggests a correlation between aging and cancer as well. Predicted ages obtained by...

The Synthetic Biology Platform is designed to program comprehensive biosynthesis development in one place. The goal was to develop a platform that could program comprehensive biosynthesis development in one place, and since then, it has become a reality. The Synthetic Biology Platform is a disruptive technology platform focusing on synthetic biology, which can contribute to the advancement of diverse areas, including but not limited to industrial biotechnology, pharmaceutical, agriculture, and h...

Laboratory equipment is a general term for the various instruments, containers and other tools needed for operation, synthesis, and analysis in various laboratories. The equipment helps researchers to observe, test, experiment or analyze data to confirm the authenticity or rationality of scientific hypotheses. According to the scope of application, laboratory equipment can be divided into general equipment and specialized equipment.General laboratory equipment includes freezers, incubators, shak...

Matexcel, a quality provider of products and services in material sciences, recently released Egg Shell Hydroxyapatite that can be integrated into biomedical and environmental projects. Egg Shell Hydroxyapatite is a type of hydroxyapatite that is derived from the shells of eggs. Hydroxyapatite is a naturally occurring form of calcium and phosphate, which is a major component of bone and hard tissues. When egg shells, which are rich in calcium, are processed correctly, they can create this valuab...

Bioink is a solution of a biomaterial or a mixture of several biomaterials in the hydrogel form, usually encapsulating living cells, and/or bioactive molecules. For bioprinting, bioinks are essential components, and are cross-linked or stabilized during or immediately after the bioprinting to create the final shapes of the intended tissue constructs.The selection of appropriate bioink depends on the specific application and the type of cells as well as the bioprinter to be used. An ideal bioink ...